●ISSO Jobs

Careers in System Security & Compliance

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●47 jobs posted in the last 2 weeks

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196 jobs available
100% ISSO Roles
Security & Compliance Focused

Latest Opportunities

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Contract Security, Compliance, and Access Analyst
General Dynamics Information Technology
On-siteFULL TIME$85,093 – $109,250SENIOR
1 day ago
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Cybersecurity Systems Engineer, ISSO, with an active TS/SCI with a Full Scope Polygraph Security Clearance Required, Onsite
Parallel Partners
On-siteFULL TIME$150,000 – $190,000EXECUTIVE
3 days ago
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Cybersecurity Systems Engineer, ISSO, with an active TS/SCI with a Full Scope Polygraph Security Clearance Required, Onsite
Next Step Systems
On-siteFULL TIME$150,000 – $190,000EXECUTIVE
3 days ago
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Cybersecurity Systems Engineer, ISSO, with an active TS/SCI with a Full Scope Polygraph Security Clearance Required, Onsite
Ginas Tech Jobs
On-siteFULL TIME$150,000 – $190,000EXECUTIVE
3 days ago
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Security & Compliance Administrator
Booz Allen Hamilton
On-siteFULL TIME$99,000 – $225,000MID
3 days ago
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System Engineer 6 (ISSO)
Wyetech
On-siteFULL TIME$97 – $132EXECUTIVE
3 days ago
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Cybersecurity Compliance Analyst
TX-HHSC-DSHS-DFPS
On-siteFULL TIME$5,797 – $8,416SENIOR
3 days ago
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Systems Engineer – Microsoft 365 Security & Compliance / Endpoint Security Engineer (GCC)
Leidos
On-siteFULL TIME$107,900 – $195,050EXECUTIVE
3 days ago
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ISSM / Site Lead
General Dynamics Mission Systems, Inc
On-siteFULL TIME$123,069 – $129,799SENIOR
3 days ago
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Senior Specialist, Cyber Intelligence (ISSO)
L3HHCM20
On-siteFULL TIME$92,500 – $171,500SENIOR
4 days ago
Showing 10 of 196 jobs. View all jobs →

Career Insights & Resources

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Career Advice
What Does an Information System Security Officer (ISSO) Do?
If you’ve ever come across the role Information System Security Officer (ISSO) and wondered what it actually involves, you’re not alone. It’s one of those job titles that sounds technical—and it is—but at its core, it’s about protecting systems, data, and people from cyber threats.
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Corey Philip·Apr 25, 2026·4 min read

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